ISO 9001 CERTIFIED QMS · UKAS-VERIFIED THIRD-PARTY TESTING · HPLC-VERIFIED PER BATCH
✓ HPLC-verified per batch ✓ CoA with every order ✓ 2-3 day Ireland delivery ✓ ISO 9001 certified

PRODUCTS SOLD ON PEPTIDESLABIRELAND.COM ARE FOR RESEARCH PURPOSES ONLY AND ARE NOT FOR HUMAN OR VETERINARY USE.

Fast Ireland delivery — dispatched to Dublin, Cork, Galway, Limerick and nationwide.

Melanotan-2 (MT-2) — Ireland Research Reference (2026)

By the Peptides Lab Ireland research team · Updated July 2026 · Research use only

Melanotan-2 (MT-2, Melanotan II) is a synthetic cyclic heptapeptide melanocortin receptor agonist studied in preclinical pigmentation, appetite and reproductive-neuroendocrinology research. This reference is for Irish research groups working with MT-2 in preclinical protocols.

What is Melanotan-2?

MT-2 is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) engineered for higher potency, longer half-life and non-selective melanocortin receptor engagement. It is a cyclic heptapeptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂) that binds MC1R, MC3R, MC4R and MC5R.

  • Molecular formula: C₅₀H₆₉N₁₅O₉
  • Molecular weight: ≈ 1024.2 Da
  • CAS number: 121062-08-6
  • Receptors: MC1R, MC3R, MC4R, MC5R

Research applications

Preclinical research literature on MT-2 covers:

  • Melanocortin receptor pharmacology — non-selective MC1-5R receptor engagement studies
  • Pigmentation research — MC1R-driven melanogenesis in dermal biology models
  • Appetite research . MC4R-driven feeding-behaviour research
  • Reproductive neuroendocrinology , MC4R central circuits
  • Comparative studies vs PT-141 (bremelanotide), which has MSH activity removed

MT-2 vs MT-1 vs PT-141 , the three melanocortin research compounds

MT-1 MT-2 PT-141
Receptor selectivity Broad (MC1-5R) Broad (MC1-5R) MC4R > MC3R > MC1R
Pigmentation activity Yes Yes (high) Reduced
Primary research focus Pigmentation Pigmentation + appetite Reproductive/CNS
Structure Linear 13aa Cyclic heptapeptide Cyclic heptapeptide

Reconstitution reference typical 10 mg MT-2 vial

Diluent Working concentration Volume for common research doses
1.0 ml bac water 10 mg/ml 250 µg → 25 µl · 500 µg → 50 µl · 1 mg → 100 µl
2.0 ml bac water 5 mg/ml 250 µg → 50 µl · 500 µg → 100 µl · 1 mg → 200 µl
5.0 ml bac water 2 mg/ml 250 µg → 125 µl · 500 µg → 250 µl · 1 mg → 500 µl

Full technique in our reconstitution guide. Reconstituted MT-2 is stable at 2–8 °C for approximately 3–4 weeks.

Regulatory context , with Ireland

MT-2 isn’t approved as a medicinal product in Ireland or the EU. It is supplied strictly for in-vitro laboratory research and educational use. See our HPRA regulations guide.

Sourcing MT-2 in Ireland

Peptides Lab Ireland stocks HPLC-verified MT-2 with per-batch Certificate of Analysis. See the product page. Independent testing by Optima Labs.

Related research guides

For laboratory research use only. Not intended for human or veterinary use.

Picture of Emma Louise

Emma Louise

Chief Compliance Officer at Peptides Lab Ireland. Emma Louise leads regulatory compliance, HPRA framework interpretation, batch quality documentation and editorial standards for the Peptides Lab Ireland research reference library. All research guides are reviewed under her editorial oversight.
99% Purity Guarantee
Trusted By Researchers
★★★★★
Celebrating 500,000 Orders
Third party verified

Receive News

Subscribe for the Updates!