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Tesamorelin — Ireland Research Reference (2026)

Le foireann taighde Peptides Lab Ireland · Nuashonraithe Iúil 2026 · Úsáid taighde amháin

Tesamorelin is one of the most extensively characterised full-length GHRH receptor agonist research compounds. Unlike Sermorelin (a GHRH(1-29) fragment) or CJC-1295, Tesamorelin is a full-length 44 amino acid GHRH analogue with a trans-3-hexenoic acid modification for enzymatic stability. This reference is for Irish research groups working with Tesamorelin in GH-axis research.

Tesamorelin structure and pharmacology

  • Class: Full-length GHRH(1-44) analogue with N-terminal modification
  • Modification: Trans-3-hexenoic acid at the N-terminus (enhances enzymatic stability)
  • Amino acids: 44
  • Receptor: GHRH receptor (GHRHR) at pituitary somatotrophs
  • Molecular weight: ≈ 5196 Da

Research applications

The Tesamorelin research literature covers:

  • GHRH receptor pharmacology , canonical receptor engagement and downstream cAMP signalling
  • GH-axis research comparative studies against Sermorelin (fragment), CJC-1295 (modified) and native GHRH
  • Metabolic research , with visceral adipose tissue biology in preclinical metabolic protocols
  • IGF-1 axis studies — downstream GH → IGF-1 signalling research
  • Body composition research — comparative body-composition biology models

Tesamorelin vs other GHRH-class research compounds

Compound Length Modification Half-life profile
Native GHRH 44 aa Faic Very short (minutes)
Sermorelin (GHRH 1-29) 29 aa Amidated C-terminus Short
CJC-1295 without DAC 29 aa N-terminal modifications Short
CJC-1295 with DAC 29 aa DAC (albumin binding) Long
Tesamorelin 44 aa (full-length) Trans-3-hexenoic acid N-terminal Extended

Athmhúnlú

Tesamorelin reconstitutes with bacteriostatic water. See our reconstitution guide. Full-length peptides warrant extra care during reconstitution . Swirl gently, never shake. Reconstituted Tesamorelin is stable at 2–8 °C for approximately 2–3 weeks.

Regulatory context , Ireland

Tesamorelin is supplied strictly for in-vitro laboratory research and educational use. See our HPRA regulations guide.

Sourcing Tesamorelin in Ireland

Peptides Lab Ireland stocks HPLC-verified Tesamorelin with per-batch Certificate of Analysis. See the product page.

Related research guides

For laboratory research use only. Not intended for human or veterinary use.

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Emma Louise

Chief Compliance Officer at Peptides Lab Ireland. Emma Louise leads regulatory compliance, HPRA framework interpretation, batch quality documentation and editorial standards for the Peptides Lab Ireland research reference library. All research guides are reviewed under her editorial oversight.

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