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Ipamorelin + CJC-1295 Dosing Reference — Ireland Research Guide 2026

Le foireann taighde Peptides Lab Ireland · Nuashonraithe Iúil 2026 · Úsáid taighde amháin

Ipamorelin and CJC-1295 are the two peptides most commonly paired in growth-hormone (GH) axis research. Ipamorelin engages ghrelin/growth hormone secretagogue receptor (GHS-R1a) signalling; CJC-1295 engages the GHRH receptor. Combined, they activate two complementary pathways in GH-axis research protocols. This reference sets out reconstitution and dosing details for Irish research groups.

The compounds

Ipamorelin

  • Selective GHS-R1a (ghrelin receptor) agonist
  • Synthetic pentapeptide
  • Standard Peptides Lab Ireland presentation: 2 mg per vial

CJC-1295 without DAC (Modified GRF 1-29)

  • GHRH receptor agonist , pulsatile pharmacokinetic profile
  • Short-acting GHRH analogue
  • Standard presentation: 2 mg per vial

CJC-1295 with DAC (Drug Affinity Complex)

  • GHRH receptor agonist with albumin-binding modification for extended half-life
  • Long-acting GHRH analogue (research-context)
  • Standard presentation: 2 mg per vial

Reconstitution reference — 2 mg vial (each)

Bacteriostatic water added Working concentration Volume for common doses
1.0 ml 2 mg/ml (2000 µg/ml) 100 µg → 50 µl · 200 µg → 100 µl · 500 µg → 250 µl
2.0 ml 1 mg/ml (1000 µg/ml) 100 µg → 100 µl · 200 µg → 200 µl · 500 µg → 500 µl
4.0 ml 0.5 mg/ml (500 µg/ml) 100 µg → 200 µl · 200 µg → 400 µl

Combined pre-formulated blend

Peptides Lab Ireland stocks a pre-formulated CJC-1295 without DAC + Ipamorelin blend (5 mg + 5 mg per vial). Reconstitution of the blend:

Bacteriostatic water added Working concentration (combined)
1.0 ml 5 mg + 5 mg per ml
2.0 ml 2.5 mg + 2.5 mg per ml
5.0 ml 1 mg + 1 mg per ml

Reconstitution technique

Standard technique full detail in our reconstitution guide. Both compounds tolerate bacteriostatic water reconstitution and are stable at 2–8 °C for approximately 3–4 weeks post-reconstitution.

Research applications — GH axis

Preclinical research using Ipamorelin + CJC-1295 typically examines:

  • GHS-R1a and GHRH receptor cross-talk in somatotroph biology
  • IGF-1 axis activation and downstream signalling
  • Growth-hormone-mediated tissue biology research
  • Comparative signalling with other GH secretagogues (GHRP-2, GHRP-6, Hexarelin, Sermorelin, Tesamorelin)

CJC-1295 with DAC vs without DAC , research protocol choice

  • Without DAC . Shorter half-life, more pulsatile receptor engagement, closer to endogenous GHRH pulse pattern. Preferred for research questions about pulse biology.
  • With DAC , extended half-life via albumin binding. Steady-state receptor engagement. Preferred for continuous-exposure research protocols.

Sourcing in Ireland

Related research guides

For laboratory research use only. Not intended for human or veterinary use.

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Emma Louise

Chief Compliance Officer at Peptides Lab Ireland. Emma Louise leads regulatory compliance, HPRA framework interpretation, batch quality documentation and editorial standards for the Peptides Lab Ireland research reference library. All research guides are reviewed under her editorial oversight.

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